Human Cell Modeling for Cardiovascular Diseases

Endothelial Progenitor Cell Dysfunction in Polycystic Ovary Syndrome: Implications for The Genesis of Cardiovascular Diseases

Stem Cells Application in Modeling of Human Genetic Diseases

The use of animal models in modeling of human genetic disease has many advantages. In some cases, however, this method may not be applicable due to some limitations, such as differences in tissue composition, anatomy and physiology of humans and animals. Isogenic human disease models are a population of cells that are selected or engineered to model a specific genetic disease, in vitro. They ar...

Behavioral risk factors for cardiovascular diseases in Bonab city employees

Introduction:‎‏ ‏Cardiovascular diseases are causes of death in many industrialized countries. ‎This disease is among the most common, serious and deadly diseases in Iran.‎  Objective:‎‏ ‏This study was performed to determine some of the behavioral risk factors ‎associated with cardiovascular diseases in Bonab city staffs. ‎ Methods:‎‏ ...

Challenges for treatment of cardiovascular diseases based on stem cells

Introduction: Cardiovascular diseases (CVD) are the primary cause of death worldwide, and the development of scar tissue in myocardium and also the irreversible destruction of cardiomyocytes are the main factors in their development. There are still limitations in medical treatment of CVD, despite the advances in the field of drug therapy and surgery for CVD. In recent years, research on stem c...

Novel Possible Biomarkers for the Cardiovascular Diseases Prognosis

Cardiovascular disease (CVD), especially heart failure (HF) as its common final pathway, is the leading cause of morbidity and mortality worldwide. Furthermore, oxidative and inflammatory processes represent fundamental underlying mechanisms for the development and progression of HF. Of interest, in recent years the development of markers with diagnostic and prognostic value for this pathology ...